Tmlhe - trimethyllysine hydroxylase, epsilon Gene

Also Known as Tmlh

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170898

Summary

Enables trimethyllysine dioxygenase activity. Predicted to be involved in carnitine biosynthetic process and negative regulation of oxidoreductase activity. Located in mitochondrion. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human TMLHE (trimethyllysine hydroxylase, epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Tmlhe Products (1)

mRNA Protein Name
NM_133387.2 NP_596878.2 trimethyllysine dioxygenase, mitochondrial

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables trimethyllysine dioxygenase activity IDA
IDA: Inferred from direct assay
11431483 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trimethyllysine dioxygenase, mitochondrial

  • TML dioxygenase

  • TML hydroxylase

  • TML-alpha-ketoglutarate dioxygenase

  • TMLD

  • epsilon-trimethyllysine 2-oxoglutarate dioxygenase

  • epsilon-trimethyllysine hydroxylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14758 TMLHE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmlhe NCBI NCBI:55217