Lyl1 - lymphoblastomic leukemia 1 Gene

Also Known as Lyl-1; bHLHa18

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17095

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in B cell differentiation and definitive hemopoiesis. Predicted to be located in nucleus. Is expressed in brain; genitourinary system; heart; liver; and thymus primordium. Human ortholog(s) of this gene implicated in T-cell acute lymphoblastic leukemia. Orthologous to human LYL1 (LYL1 basic helix-loop-helix family member). [provided by Alliance of Genome Resources, Apr 2022]

Lyl1 Products (1)

mRNA Protein Name
NM_008535.2 NP_032561.2 protein lyl-1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
16514064 MGI
involved in definitive hemopoiesis IMP
IMP: Inferred from mutant phenotype
16514064 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein lyl-1

  • lymphoblastic leukemia-derived sequence 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07912 LYL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lyl1 NCBI NCBI:4066