Atp12a - ATPase H+/K+ transporting non-gastric alpha2 subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171028

Summary

Contributes to P-type potassium:proton transporter activity. Involved in response to metal ion and response to organic cyclic compound. Located in apical plasma membrane. Biomarker of hypokalemia. Orthologous to human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Atp12a Products (2)

mRNA Protein Name
NM_001301664.1 NP_001288593.1 potassium-transporting ATPase alpha chain 2 isoform b
NM_133517.2 NP_598201.2 potassium-transporting ATPase alpha chain 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to P-type potassium:proton transporter activity IDA
IDA: Inferred from direct assay
16046397 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9950762 RGD
Biological Process GO Annotation Evidence References Source
involved in response to metal ion IDA
IDA: Inferred from direct assay
16046397 RGD
involved in response to organic cyclic compound IDA
IDA: Inferred from direct assay
16046397 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
9950762 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium-transporting ATPase alpha chain 2

  • ATPase, H+/K+ transporting, nongastric, alpha polypeptide

  • H-K-ATPase alpha 2

  • HK alpha 2

  • hydrogen/potassium-exchanging ATPase 12A

  • non-gastric H(+)/K(+) ATPase subunit alpha

  • non-gastric Na(+)/K(+) ATPase subunit alpha

  • proton pump

  • sodium pump

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01177 ATP12A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp12a NCBI NCBI:479