Mlxipl - MLX interacting protein-like Gene

Also Known as ChREBP; WS-bHLH; Wbscr14; bHLHd14

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171078

Summary

Enables DNA-binding transcription factor activity; protein kinase binding activity; and sequence-specific DNA binding activity. Involved in several processes, including energy homeostasis; fatty acid homeostasis; and regulation of nucleobase-containing compound metabolic process. Located in cytosol and nucleus. Orthologous to human MLXIPL (MLX interacting protein like). [provided by Alliance of Genome Resources, Apr 2022]

Mlxipl Products (2)

mRNA Protein Name
NM_001393706.1 NP_001380635.1 carbohydrate-responsive element-binding protein isoform 1
NM_133552.2 NP_598236.2 carbohydrate-responsive element-binding protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
11724780 RGD
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11724780 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
20025850 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
11724780 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11724780 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
20025850 RGD
involved in energy homeostasis IMP
IMP: Inferred from mutant phenotype
11724780 RGD
involved in fatty acid homeostasis IMP
IMP: Inferred from mutant phenotype
11724780 RGD
involved in regulation of glycolytic process IDA
IDA: Inferred from direct assay
11724780 RGD
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11724780 RGD
involved in response to glucose IDA
IDA: Inferred from direct assay
11470916 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
26394137 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
25943649 RGD
involved in response to vitamin B3 IEP
IEP: Inferred from expression pattern
19878707 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
20025850 RGD
located in nucleus IDA
IDA: Inferred from direct assay
20025850 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbohydrate-responsive element-binding protein

  • MLX interactor

  • WS basic-helix-loop-helix leucine zipper protein

  • Williams-Beuren syndrome chromosomal region 14 protein

  • Williams-Beuren syndrome chromosome region 14 homolog

  • class D basic helix-loop-helix protein 14

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08505 MLXIPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21156 Mlxipl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27672 Mlxipl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mlxipl NCBI NCBI:51085