Mcoln3 - mucolipin 3 Gene

Also Known as Va; TRPML3; 6720490O21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 171166

Summary

Predicted to enable NAADP-sensitive calcium-release channel activity. Acts upstream of or within inner ear auditory receptor cell differentiation; locomotory behavior; and sensory perception of sound. Located in cytoplasm and plasma membrane. Is expressed in cochlea; olfactory epithelium; and vibrissa. Orthologous to human MCOLN3 (mucolipin TRP cation channel 3). [provided by Alliance of Genome Resources, Apr 2022]

Mcoln3 Products (1)

mRNA Protein Name
NM_134160.1 NP_598921.1 mucolipin-3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables monoatomic anion channel activity IDA
IDA: Inferred from direct assay
17989217 MGI
enables potassium channel activity IDA
IDA: Inferred from direct assay
17989217 MGI
enables sodium channel activity IDA
IDA: Inferred from direct assay
17989217 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within inner ear auditory receptor cell differentiation IMP
IMP: Inferred from mutant phenotype
12403827 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
16962269 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12403827 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12403827 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucolipin-3

  • transient receptor potential channel mucolipin 3

  • varitint-waddler

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08246 MCOLN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcoln3 NCBI NCBI:55283