2. Gene
  3. Mcoln3 - mucolipin 3 Gene

Mcoln3 - mucolipin 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Va; TRPML3; 6720490O21Rik

Gene ID: 171166 | Gene type: protein coding

About Mcoln3

Summary

Predicted to enable NAADP-sensitive calcium-release channel activity. Acts upstream of or within inner ear auditory receptor cell differentiation; locomotory behavior; and sensory perception of sound. Located in cytoplasm and plasma membrane. Is expressed in cochlea; olfactory epithelium; and vibrissa. Orthologous to human MCOLN3 (mucolipin TRP cation channel 3). [provided by Alliance of Genome Resources, Apr 2022]

Mcoln3 Products(1)

mRNA Protein Name
NM_134160.1 NP_598921.1 mucolipin-3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables monoatomic anion channel activity IDA
IDA: Inferred from direct assay
17989217 MGI
enables potassium channel activity IDA
IDA: Inferred from direct assay
17989217 MGI
enables sodium channel activity IDA
IDA: Inferred from direct assay
17989217 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within inner ear auditory receptor cell differentiation IMP
IMP: Inferred from mutant phenotype
12403827 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
16962269 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12403827 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12403827 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucolipin-3

transient receptor potential channel mucolipin 3

varitint-waddler

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08246 MCOLN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcoln3 NCBI NCBI:55283