Pou4f2 - POU class 4 homeobox 2 Gene

Also Known as Brn3b; Brn-3B; Brn-3.2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171355

Summary

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; p53 binding activity; and promoter-specific chromatin binding activity. Involved in several processes, including cellular response to oxygen levels; positive regulation of cardiac muscle cell apoptotic process; and spermatogenesis. Predicted to be located in cytoplasm; euchromatin; and nuclear speck. Predicted to be part of transcription regulator complex. Orthologous to human POU4F2 (POU class 4 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Pou4f2 Products (1)

mRNA Protein Name
NM_134355.1 NP_599182.1 POU domain, class 4, transcription factor 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to oxygen levels IMP
IMP: Inferred from mutant phenotype
25356872 RGD
involved in positive regulation of cardiac muscle cell apoptotic process IMP
IMP: Inferred from mutant phenotype
25356872 RGD
involved in regulation of gene expression IMP
IMP: Inferred from mutant phenotype
25356872 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
11470235 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain, class 4, transcription factor 2

  • brain-3B

  • brain-specific homeobox/POU domain protein 3B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10905 POU4F2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou4f2 NCBI NCBI:5458