2. Gene
  3. Ppp3cc - protein phosphatase 3 catalytic subunit gamma Gene

Ppp3cc - protein phosphatase 3 catalytic subunit gamma Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 171378 | Gene type: protein coding

About Ppp3cc

Summary

Predicted to enable Calmodulin binding activity and calmodulin-dependent protein Phosphatase activity. Involved in brain development and positive regulation of synaptic vesicle endocytosis. Located in presynapse. Is active in glutamatergic synapse. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human PPP3CC (protein Phosphatase 3 catalytic subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ppp3cc Products(1)

mRNA Protein Name
NM_134367.1 NP_599194.1 serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15120593 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
26627835 RGD
involved in regulation of synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
26627835 RGD
involved in regulation of synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
26627835 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
26627835 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
26627835 RGD
located in presynapse IDA
IDA: Inferred from direct assay
26627835 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

protein phosphatase 3, catalytic subunit, gamma isozyme

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11025 PPP3CC Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp3cc NCBI NCBI:5533