2. Gene
  3. H1f8 - H1.8 linker histone Gene

H1f8 - H1.8 linker histone Gene

  • Gene
  • Protein
Mus musculus

Also known as H1-8; H1.8; H1fo; H1oo; H1foo

Gene ID: 171506 | Gene type: protein coding

About H1f8

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes and the encoded protein is expressed only in oocytes. [provided by RefSeq, Oct 2015]

H1f8 Products(4)

mRNA Protein Name
NM_001346702.1 NP_001333631.1 histone H1.8 isoform 2
NM_138311.3 NP_612184.1 histone H1.8 isoform 1
NM_001346702.1 NP_001333631.1 histone H1.8 isoform 2
NM_138311.3 NP_612184.1 histone H1.8 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables nucleosomal DNA binding IDA
IDA: Inferred from direct assay
22868987 MGI
enables structural constituent of chromatin IDA
IDA: Inferred from direct assay
22868987 MGI
Biological Process GO Annotation Evidence Reference Source
involved in epigenetic regulation of gene expression IMP
IMP: Inferred from mutant phenotype
22868987 MGI
Cellular Component GO Annotation Evidence Reference Source
located in female germ cell nucleus IDA
IDA: Inferred from direct assay
11171391 MGI
NOT located in nucleolus IDA
IDA: Inferred from direct assay
22868987 MGI
located in nucleus IDA
IDA: Inferred from direct assay
22868987 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone H1.8

H1 histone family, member O, oocyte-specific

histone H1oo

oocyte-specific histone H1

oocyte-specific linker histone H1