Nme7 - NME/NM23 family member 7 Gene

Also Known as Nm23-M7; Nm23-r7; D530024H21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 171567

Summary

Predicted to enable ATP binding activity; metal ion binding activity; and nucleoside diphosphate kinase activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; ciliary receptor clustering involved in smoothened signaling pathway; and intraciliary transport. Located in centrosome and ciliary basal body. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study hydrocephalus. Orthologous to human NME7 (NME/NM23 family member 7). [provided by Alliance of Genome Resources, Apr 2022]

Nme7 Products (3)

mRNA Protein Name
NM_001293313.1 NP_001280242.1 nucleoside diphosphate kinase 7 isoform 1
NM_138314.4 NP_612187.2 nucleoside diphosphate kinase 7 isoform 1
NM_178071.6 NP_835172.1 nucleoside diphosphate kinase 7 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
21746835 MGI
acts upstream of or within epithelial cilium movement involved in extracellular fluid movement IMP
IMP: Inferred from mutant phenotype
21746835 MGI
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
acts upstream of or within intraciliary transport IMP
IMP: Inferred from mutant phenotype
21289087 MGI
acts upstream of or within left/right pattern formation IMP
IMP: Inferred from mutant phenotype
20080492 MGI
acts upstream of or within receptor clustering IMP
IMP: Inferred from mutant phenotype
21289087 MGI
Cellular Component GO Annotation Evidence References Source
is active in axonemal A tubule inner sheath IDA
IDA: Inferred from direct assay
37295417 MGI
located in axonemal microtubule IDA
IDA: Inferred from direct assay
37295417 MGI
located in centrosome IDA
IDA: Inferred from direct assay
21289087 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
21289087 MGI
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleoside diphosphate kinase 7

  • NDK 7

  • NDP kinase 7

  • non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

  • nucleoside-diphosphate kinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09378 NME7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nme7 NCBI NCBI:29922