Mcm4 - minichromosome maintenance complex component 4 Gene

Also Known as 19G; Cdc21; Mcmd4; mcdc21; mKIAA4003

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17217

Summary

Enables single-stranded DNA binding activity. Contributes to DNA helicase activity. Acts upstream of or within DNA unwinding involved in DNA replication. Predicted to be located in nucleoplasm. Predicted to be part of MCM complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; future brain; limb; metanephros; and myocardium layer. Human ortholog(s) of this gene implicated in immunodeficiency 54. Orthologous to human MCM4 (minichromosome maintenance complex component 4). [provided by Alliance of Genome Resources, Apr 2022]

Mcm4 Products (1)

mRNA Protein Name
NM_008565.3 NP_032591.3 DNA replication licensing factor MCM4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to DNA helicase activity IDA
IDA: Inferred from direct assay
15917436 MGI
contributes to DNA helicase activity IMP
IMP: Inferred from mutant phenotype
10567526 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15917436 MGI
contributes to single-stranded DNA binding IMP
IMP: Inferred from mutant phenotype
10567526 MGI
enables single-stranded DNA binding IPI
IPI: Inferred from physical interaction
15917436 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA unwinding involved in DNA replication IPI
IPI: Inferred from physical interaction
15917436 MGI
Cellular Component GO Annotation Evidence References Source
part of MCM complex IDA
IDA: Inferred from direct assay
10567526 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA replication licensing factor MCM4

  • CDC21 homolog

  • P1-CDC21

  • mini chromosome maintenance deficient 4 homolog

  • minichromosome maintenance deficient 4 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08237 MCM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcm4 NCBI NCBI:4173