Mdm1 - transformed mouse 3T3 cell double minute 1 Gene

Also Known as Arrd2; Mdm-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17245

Summary

Predicted to enable microtubule binding activity. Acts upstream of or within photoreceptor cell maintenance and retina development in camera-type eye. Located in centriole; centrosome; and non-motile cilium. Is expressed in brain ependyma; retina inner nuclear layer; and retina outer nuclear layer. Used to study age related macular degeneration. Orthologous to human MDM1 (Mdm1 nuclear protein). [provided by Alliance of Genome Resources, Apr 2022]

Mdm1 Products (4)

mRNA Protein Name
NM_001162904.1 NP_001156376.1 nuclear protein MDM1 isoform 3
NM_001162905.1 NP_001156377.1 nuclear protein MDM1 isoform 4
NM_010785.2 NP_034915.2 nuclear protein MDM1 isoform 1
NM_148922.3 NP_683724.2 nuclear protein MDM1 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
21052544 MGI
Cellular Component GO Annotation Evidence References Source
located in centriole IDA
IDA: Inferred from direct assay
26337392 MGI
located in centrosome IDA
IDA: Inferred from direct assay
23300604 MGI
located in non-motile cilium IDA
IDA: Inferred from direct assay
23300604 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear protein MDM1

  • double minute 1

  • mdm4 transformed 3T3 cell double minute 1 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15997 (-)-U-50488 hydrochloride Inhibitor 99.71% Unkown
HY-RS08263 MDM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-155407 ALR-6 Antagonist / Unkown
HY-155408 ALR-27 Antagonist / Unkown
HY-RS18772 Mdm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25260 Mdm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mdm1 NCBI NCBI:56890