Rdh11 - retinol dehydrogenase 11 Gene

Also Known as Mdt1; Psdr1; SCALD; ralR1; Arsdr1; CGI-82; HCBP12; M42C60; Ube-1c; UBE-1c1; 2610319N22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17252

Summary

Enables aldehyde dehydrogenase (NADP+) activity. Involved in cellular detoxification of aldehyde; retinol metabolic process; and visual perception. Acts upstream of or within adaptation of rhodopsin mediated signaling. Located in photoreceptor inner segment. Is expressed in cerebral cortex ventricular layer and diencephalon. Orthologous to human RDH11 (retinol dehydrogenase 11). [provided by Alliance of Genome Resources, Apr 2022]

Rdh11 Products (3)

mRNA Protein Name
NM_001362269.1 NP_001349198.1 retinol dehydrogenase 11 isoform 2
NM_001362270.1 NP_001349199.1 retinol dehydrogenase 11 isoform 3
NM_021557.6 NP_067532.2 retinol dehydrogenase 11 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables aldehyde dehydrogenase (NADP+) activity IDA
IDA: Inferred from direct assay
12807874 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular detoxification of aldehyde IDA
IDA: Inferred from direct assay
12807874 MGI
involved in retinol metabolic process IMP
IMP: Inferred from mutant phenotype
29567832 MGI
involved in visual perception IMP
IMP: Inferred from mutant phenotype
15790565 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
15790565 MGI
NOT located in photoreceptor outer segment membrane IDA
IDA: Inferred from direct assay
15790565 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinol dehydrogenase 11

  • all-trans and 9-cis

  • androgen-regulated short-chain dehydrogenase/reductase 1

  • cell line MC/9.IL4 derived transcript 1

  • cell line MC/9.IL4-derived protein 1

  • prostate short-chain dehydrogenase/reductase 1

  • retinal reductase 1

  • short-chain aldehyde dehydro

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11799 RDH11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rdh11 NCBI NCBI:51109