Mocs2 - molybdenum cofactor synthesis 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17434

Summary

Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. Based on experiments with the human molybdopterin synthase ortholog, they are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008]

Mocs2 Products (3)

mRNA Protein Name
NM_001113374.1 NP_001106845.1 molybdopterin synthase sulfur carrier subunit isoform Mocs2B
NM_001113375.1 NP_001106846.1 molybdopterin synthase sulfur carrier subunit isoform Mocs2B2
NM_013826.3 NP_038854.2 molybdopterin synthase sulfur carrier subunit isoform Mocs2A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence References Source
involved in molybdopterin cofactor biosynthetic process IMP
IMP: Inferred from mutant phenotype
27138983 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

molybdopterin synthase sulfur carrier subunit

  • MOCS2B

  • molybdenum cofactor synthesis protein 2 large subunit

  • molybdenum cofactor synthesis protein 2B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08581 MOCS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mocs2 NCBI NCBI:4338