2. Gene
  3. Mpv17 - MpV17 mitochondrial inner membrane protein Gene

Mpv17 - MpV17 mitochondrial inner membrane protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tg.Mpv17

Gene ID: 17527 | Gene type: protein coding

About Mpv17

Summary

Predicted to enable channel activity. Involved in several processes, including cellular response to reactive oxygen species; glomerular basement membrane development; and regulation of mitochondrial DNA metabolic process. Acts upstream of or within Reactive Oxygen Species metabolic process and sensory perception of sound. Located in mitochondrion and peroxisome. Used to study autosomal recessive Alport syndrome; mitochondrial DNA depletion syndrome 3; and nephrotic syndrome. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2EE and mitochondrial DNA depletion syndrome 6. Orthologous to human MPV17 (mitochondrial inner membrane protein MPV17). [provided by Alliance of Genome Resources, Apr 2022]

Mpv17 Products(5)

mRNA Protein Name
NM_001294322.1 NP_001281251.1 protein Mpv17 isoform 2
NM_001294324.1 NP_001281253.1 protein Mpv17 isoform 1
NM_001310527.1 NP_001297456.1 protein Mpv17 isoform 1
NM_001310528.1 NP_001297457.1 protein Mpv17 isoform 3
NM_008622.6 NP_032648.1 protein Mpv17 isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to reactive oxygen species IMP
IMP: Inferred from mutant phenotype
16041630 MGI
involved in glomerular basement membrane development IMP
IMP: Inferred from mutant phenotype
16041630 MGI
involved in inner ear development IMP
IMP: Inferred from mutant phenotype
16041630 MGI
acts upstream of or within reactive oxygen species metabolic process IDA
IDA: Inferred from direct assay
7957077 MGI
involved in regulation of mitochondrial DNA metabolic process IMP
IMP: Inferred from mutant phenotype
26760297 MGI
involved in regulation of reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
16041630 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IMP
IMP: Inferred from mutant phenotype
16582910 MGI
located in peroxisome IDA
IDA: Inferred from direct assay
7957077 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Mpv17

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08631 MPV17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08632 MPV17L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17001 Mal Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17732 Ucn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mpv17 NCBI NCBI:4358