2. Gene
  3. Polr2k - polymerase (RNA) II (DNA directed) polypeptide K Gene

Polr2k - polymerase (RNA) II (DNA directed) polypeptide K Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MafY; Mt1a; RPB12; RPABC4; RPB7.0; RPB10alpha; ABC10-alpha

Gene ID: 17749 | Gene type: protein coding

About Polr2k

Summary

Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and zinc ion binding activity. Acts upstream of or within transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Is expressed in several structures, including cerebral cortex; nose; submandibular gland primordium; thymus primordium; and tooth. Orthologous to human POLR2K (RNA polymerase II, I and III subunit K). [provided by Alliance of Genome Resources, Apr 2022]

Polr2k Products(2)

mRNA Protein Name
NM_001039368.2 NP_001034457.1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 isoform a
NM_023127.3 NP_075616.2 DNA-directed RNA polymerases I, II, and III subunit RPABC4 isoform b
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8329119 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerases I, II, and III subunit RPABC4

metallothionein-I gene transcription activator

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10853 POLR2K Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr2k NCBI NCBI:5440