2. Gene
  3. Myef2 - myelin basic protein expression factor 2, repressor Gene

Myef2 - myelin basic protein expression factor 2, repressor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1341; 9430071B01

Gene ID: 17876 | Gene type: protein coding

About Myef2

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Predicted to be part of post-mRNA release spliceosomal complex. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; liver; sensory organ; thymus; and vertebral axis musculature. Orthologous to human MYEF2 (myelin expression factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Myef2 Products(4)

mRNA Protein Name
NM_001162417.2 NP_001155889.1 myelin expression factor 2 isoform 1
NM_001162418.2 NP_001155890.1 myelin expression factor 2 isoform 3
NM_001401843.1 NP_001388772.1 myelin expression factor 2 isoform 1
NM_010852.3 NP_034982.2 myelin expression factor 2 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
7539003 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
7539003 MGI
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7539003 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myelin expression factor 2

MEF-2

myEF-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08890 MYEF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myef2 NCBI NCBI:50804