Myf6 - myogenic factor 6 Gene

Also Known as MRF4; bHLHc4; herculin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17878

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within muscle organ development; regulation of transcription, DNA-templated; and somitogenesis. Predicted to be located in nucleus. Is expressed in several structures, including esophagus; ganglia; limb; paraxial mesenchyme; and skeletal musculature. Human ortholog(s) of this gene implicated in congenital structural myopathy. Orthologous to human MYF6 (myogenic factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Myf6 Products (1)

mRNA Protein Name
NM_008657.3 NP_032683.1 myogenic factor 6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
24361185 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within muscle tissue morphogenesis IMP
IMP: Inferred from mutant phenotype
19531352 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
7797078 MGI
acts upstream of or within positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
7720708 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
acts upstream of or within skeletal muscle tissue development IGI
IGI: Inferred from genetic interaction
19531352 MGI
acts upstream of or within skeletal muscle tissue development IMP
IMP: Inferred from mutant phenotype
7588068 MGI
acts upstream of or within somitogenesis IMP
IMP: Inferred from mutant phenotype
7588068 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myogenic factor 6

  • muscle-specific regulatory factor 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08893 MYF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myf6 NCBI NCBI:4618