Myo5b - myosin VB Gene

Also Known as mKIAA1119

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17919

Summary

Predicted to enable several functions, including ATP hydrolysis activity; ionotropic glutamate receptor binding activity; and small GTPase binding activity. Involved in modulation of chemical synaptic transmission. Located in Schaffer collateral - CA1 synapse and brush border. Is expressed in central nervous system; genitourinary system; and gut. Used to study microvillus inclusion disease. Human ortholog(s) of this gene implicated in microvillus inclusion disease. Orthologous to human MYO5B (Myosin VB). [provided by Alliance of Genome Resources, Apr 2022]

Myo5b Products (1)

mRNA Protein Name
NM_201600.2 NP_963894.1 unconventional myosin-Vb

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29880681 MGI
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
18984164 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
18984164 MGI
acts upstream of or within protein transmembrane transport IDA
IDA: Inferred from direct assay
28576874 MGI
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
18984164 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
18984164 MGI
located in brush border IDA
IDA: Inferred from direct assay
22114352 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Vb

  • myosin-Vb

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08947 MYO5B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-D3304 Cholyl-L-lysine fluorescein disodium / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo5b NCBI NCBI:4645