Neurog1 - neurogenin 1 Gene

Mus musculus

Also known as AKA; ngn1; Math4C; bHLHa6; Neurod3

Gene ID: 18014 | Gene type: protein coding

About Neurog1

Summary

Enables E-box binding activity and chromatin binding activity. Involved in positive regulation of DNA-binding transcription factor activity; positive regulation of neuron differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including inner ear morphogenesis; positive regulation of exit from mitosis; and regulation of neuron differentiation. Located in perikaryon. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human NEUROG1 (neurogenin 1). [provided by Alliance of Genome Resources, Apr 2022]

Neurog1 Products(1)

mRNA	Protein	Name
NM_010896.3	NP_035026.1	neurogenin-1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables E-box binding	IDA IDA: Inferred from direct assay	14697366	MGI
enables chromatin binding	IDA IDA: Inferred from direct assay	18007592	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	22513373	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cell fate commitment	IGI IGI: Inferred from genetic interaction	15229646	MGI
acts upstream of exit from mitosis	IMP IMP: Inferred from mutant phenotype	16145671	MGI
acts upstream of or within inner ear morphogenesis	IMP IMP: Inferred from mutant phenotype	16145671	MGI
acts upstream of or within neurogenesis	IDA IDA: Inferred from direct assay	18184563	MGI
acts upstream of or within neuron differentiation	IDA IDA: Inferred from direct assay	23288605	MGI
acts upstream of or within neuron differentiation	IMP IMP: Inferred from mutant phenotype	16145671	MGI
involved in positive regulation of DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	14697366	MGI
acts upstream of or within positive regulation of exit from mitosis	IMP IMP: Inferred from mutant phenotype	16145671	MGI
involved in positive regulation of neuron differentiation	IDA IDA: Inferred from direct assay	10648228	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	23434913	MGI
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	18007592	MGI
acts upstream of or within regulation of neuron differentiation	IGI IGI: Inferred from genetic interaction	22513373	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in neuronal cell body	IDA IDA: Inferred from direct assay	15065125	MGI
located in perikaryon	IDA IDA: Inferred from direct assay	15065125	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

neurogenin-1

NGN-1	helix-loop-helix protein mATH-4C
neurogenic basic-helix-loop-helix protein	neurogenic differentiation 3
neurogenic differentiation factor 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09228	NEUROG1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Neurog1	NCBI	NCBI:4762

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