Neurog1 - neurogenin 1 Gene

Also Known as AKA; ngn1; Math4C; bHLHa6; Neurod3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18014

Summary

Enables E-box binding activity and chromatin binding activity. Involved in positive regulation of DNA-binding transcription factor activity; positive regulation of neuron differentiation; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including inner ear morphogenesis; positive regulation of exit from mitosis; and regulation of neuron differentiation. Located in perikaryon. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human NEUROG1 (neurogenin 1). [provided by Alliance of Genome Resources, Apr 2022]

Neurog1 Products (1)

mRNA Protein Name
NM_010896.3 NP_035026.1 neurogenin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables E-box binding IDA
IDA: Inferred from direct assay
14697366 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
18007592 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22513373 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell fate commitment IGI
IGI: Inferred from genetic interaction
15229646 MGI
acts upstream of exit from mitosis IMP
IMP: Inferred from mutant phenotype
16145671 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: Inferred from mutant phenotype
16145671 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
18184563 MGI
acts upstream of or within neuron differentiation IDA
IDA: Inferred from direct assay
23288605 MGI
acts upstream of or within neuron differentiation IMP
IMP: Inferred from mutant phenotype
16145671 MGI
involved in positive regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
14697366 MGI
acts upstream of or within positive regulation of exit from mitosis IMP
IMP: Inferred from mutant phenotype
16145671 MGI
involved in positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
10648228 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23434913 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18007592 MGI
acts upstream of or within regulation of neuron differentiation IGI
IGI: Inferred from genetic interaction
22513373 MGI
Cellular Component GO Annotation Evidence References Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
15065125 MGI
located in perikaryon IDA
IDA: Inferred from direct assay
15065125 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neurogenin-1

  • NGN-1

  • helix-loop-helix protein mATH-4C

  • neurogenic basic-helix-loop-helix protein

  • neurogenic differentiation 3

  • neurogenic differentiation factor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09228 NEUROG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neurog1 NCBI NCBI:4762