2. Gene
  3. Nfkbil1 - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1 Gene

Nfkbil1 - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as IKBL; Def-7; ikappaBL

Gene ID: 18038 | Gene type: protein coding

About Nfkbil1

Summary

Acts upstream of or within I-kappaB kinase/NF-kappaB signaling. Located in cytosol and nucleus. Is expressed in embryo; eye; and heart. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human NFKBIL1 (NFKB inhibitor like 1). [provided by Alliance of Genome Resources, Apr 2022]

Nfkbil1 Products(2)

mRNA Protein Name
NM_001364909.1 NP_001351838.1 NF-kappa-B inhibitor-like protein 1 isoform 2
NM_010909.5 NP_035039.1 NF-kappa-B inhibitor-like protein 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables transcription regulator inhibitor activity IDA
IDA: Inferred from direct assay
22024480 MGI
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
22024480 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in nucleus IDA
IDA: Inferred from direct assay
22024480 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NF-kappa-B inhibitor-like protein 1

I-kappa-B-like protein

inhibitor of kappa B-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09264 NFKBIL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfkbil1 NCBI NCBI:4795