Nfs1 - nitrogen fixation gene 1 (S. cerevisiae) Gene

Also Known as m-Nfs1; m-Nfsl

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18041

Summary

Predicted to enable cysteine desulfurase activity and protein homodimerization activity. Involved in iron incorporation into metallo-sulfur cluster. Located in mitochondrial matrix and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency. Orthologous to human NFS1 (NFS1 cysteine desulfurase). [provided by Alliance of Genome Resources, Apr 2022]

Nfs1 Products (1)

mRNA Protein Name
NM_010911.2 NP_035041.2 cysteine desulfurase, mitochondrial

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in [4Fe-4S] cluster assembly IDA
IDA: Inferred from direct assay
25597503 MGI
involved in iron incorporation into metallo-sulfur cluster IDA
IDA: Inferred from direct assay
16847322 MGI
Cellular Component GO Annotation Evidence References Source
part of mitochondrial [2Fe-2S] assembly complex IDA
IDA: Inferred from direct assay
21298097 MGI
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
9738949 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
16787928 MGI
located in nucleus IDA
IDA: Inferred from direct assay
16847322 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cysteine desulfurase, mitochondrial

  • nifS-like (sic)

  • nitrogen fixation gene, yeast homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09267 NFS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21391 Nfs1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27910 Nfs1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfs1 NCBI NCBI:9054