Otog - otogelin Gene

Also Known as twt; Otgn; 4932420K09

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18419

Summary

Enables structural molecule activity. Acts upstream of or within adult locomotory behavior and sensory perception of sound. Located in cytosol and extracellular matrix. Is expressed in inner ear. Used to study autosomal recessive nonsyndromic deafness 18B. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 18B. Orthologous to human OTOG (otogelin). [provided by Alliance of Genome Resources, Apr 2022]

Otog Products (1)

mRNA Protein Name
NM_013624.2 NP_038652.2 otogelin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables structural molecule activity IMP
IMP: Inferred from mutant phenotype
10655058 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
10655058 MGI
acts upstream of or within cellular component organization IMP
IMP: Inferred from mutant phenotype
31776257 MGI
acts upstream of or within inner ear receptor cell stereocilium organization IMP
IMP: Inferred from mutant phenotype
31776257 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
31776257 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
10655058 MGI
acts upstream of or within vibrational conductance of sound to the inner ear IMP
IMP: Inferred from mutant phenotype
31776257 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
9405633 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
9405633 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

otogelin

  • twister

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09862 OTOG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Otog NCBI NCBI:340990