2. Gene
  3. Pcsk4 - proprotein convertase subtilisin/kexin type 4 Gene

Pcsk4 - proprotein convertase subtilisin/kexin type 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PC4; NEC3; SPC5; NEC 3

Gene ID: 18551 | Gene type: protein coding

About Pcsk4

Summary

Predicted to enable serine-type endopeptidase activity. Involved in fertilization and sperm capacitation. Acts upstream of or within acrosome reaction and binding activity of sperm to zona pellucida. Located in acrosomal membrane. Is expressed in early conceptus; epididymis; gonad; and neural retina. Orthologous to human PCSK4 (proprotein convertase subtilisin/kexin type 4). [provided by Alliance of Genome Resources, Apr 2022]

Pcsk4 Products(1)

mRNA Protein Name
NM_008793.2 NP_032819.1 proprotein convertase subtilisin/kexin type 4 precursor
Protein Preferred Names Protein Names

proprotein convertase subtilisin/kexin type 4

KEX2-like endoprotease 3

neuroendocrine convertase 3

prohormone convertase 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10173 PCSK4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcsk4 NCBI NCBI:54760