Pde6g - phosphodiesterase 6G, cGMP-specific, rod, gamma Gene

Also Known as Pdeg; p3AT

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18588

Summary

Predicted to enable spectrin binding activity. Acts upstream of or within positive regulation of G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of epidermal growth factor receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in photoreceptor outer segment membrane. Is expressed in retina outer nuclear layer. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in retinitis pigmentosa 57. Orthologous to human PDE6G (phosphodiesterase 6G). [provided by Alliance of Genome Resources, Apr 2022]

Pde6g Products (1)

mRNA Protein Name
NM_012065.3 NP_036197.1 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11502744 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
11502744 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
11502744 MGI
acts upstream of or within positive regulation of epidermal growth factor receptor signaling pathway IDA
IDA: Inferred from direct assay
11502744 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

  • GMP-PDE gamma

  • cGMP phosphodiesterase gamma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10236 PDE6G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde6g NCBI NCBI:5148