Pex7 - peroxisomal biogenesis factor 7 Gene

Also Known as MmPEX7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18634

Summary

Predicted to enable enzyme binding activity; peroxisome matrix targeting signal-2 binding activity; and protein homodimerization activity. Acts upstream of or within several processes, including endochondral ossification; fatty acid beta-oxidation; and protein import into peroxisome matrix. Located in cytosol. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Used to study rhizomelic chondrodysplasia punctata type 1. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and rhizomelic chondrodysplasia punctata type 1. Orthologous to human PEX7 (peroxisomal biogenesis factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Pex7 Products (2)

mRNA Protein Name
NM_001161825.1 NP_001155297.1 peroxisomal biogenesis factor 7 isoform 2
NM_008822.2 NP_032848.1 peroxisomal biogenesis factor 7 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within endochondral ossification IMP
IMP: Inferred from mutant phenotype
12915479 MGI
acts upstream of or within fatty acid beta-oxidation IMP
IMP: Inferred from mutant phenotype
12915479 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
12915479 MGI
acts upstream of or within protein import into peroxisome matrix IMP
IMP: Inferred from mutant phenotype
9090381 MGI
involved in protein import into peroxisome matrix IMP
IMP: Inferred from mutant phenotype
12915479 MGI
acts upstream of or within protein targeting to peroxisome IMP
IMP: Inferred from mutant phenotype
12915479 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
9090381 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisomal biogenesis factor 7

  • PTS2 receptor

  • peroxin-7

  • peroxisomal targeting signal 2 receptor

  • peroxisome biogenesis factor 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10354 PEX7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pex7 NCBI NCBI:5191