Pex7 - peroxisomal biogenesis factor 7 Gene

Mus musculus

Also known as MmPEX7

Gene ID: 18634 | Gene type: protein coding

About Pex7

Summary

Predicted to enable enzyme binding activity; peroxisome matrix targeting signal-2 binding activity; and protein homodimerization activity. Acts upstream of or within several processes, including endochondral ossification; fatty acid beta-oxidation; and protein import into peroxisome matrix. Located in cytosol. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Used to study rhizomelic chondrodysplasia punctata type 1. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and rhizomelic chondrodysplasia punctata type 1. Orthologous to human PEX7 (peroxisomal biogenesis factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Pex7 Products(2)

mRNA	Protein	Name
NM_001161825.1	NP_001155297.1	peroxisomal biogenesis factor 7 isoform 2
NM_008822.2	NP_032848.1	peroxisomal biogenesis factor 7 isoform 1

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within endochondral ossification	IMP IMP: Inferred from mutant phenotype	12915479	MGI
acts upstream of or within fatty acid beta-oxidation	IMP IMP: Inferred from mutant phenotype	12915479	MGI
acts upstream of or within neuron migration	IMP IMP: Inferred from mutant phenotype	12915479	MGI
acts upstream of or within protein import into peroxisome matrix	IMP IMP: Inferred from mutant phenotype	9090381	MGI
involved in protein import into peroxisome matrix	IMP IMP: Inferred from mutant phenotype	12915479	MGI
acts upstream of or within protein targeting to peroxisome	IMP IMP: Inferred from mutant phenotype	12915479	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	9090381	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

peroxisomal biogenesis factor 7

PTS2 receptor	peroxin-7
peroxisomal targeting signal 2 receptor	peroxisome biogenesis factor 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10354	PEX7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pex7	NCBI	NCBI:5191

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