2. Gene
  3. Pik3c2g - phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma Gene

Pik3c2g - phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PI3K-C2-gamma

Gene ID: 18705 | Gene type: protein coding

About Pik3c2g

Chromosome 6: 139,564,219-139,915,010 forward strand.GRCm39:CM000999.3

This gene has 15 transcripts (splice variants), 183 orthologues, 9 paralogues and is associated with 13 phenotypes. Biased expression in kidney adult (RPKM 1.6), liver adult (RPKM 1.3) and 13 other tissues.

Summary

Predicted to enable 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in chemotaxis. Predicted to be located in Golgi apparatus and nuclear envelope. Predicted to be part of phosphatidylinositol 3-kinase complex. Predicted to be active in cytoplasm and plasma membrane. Is expressed in alimentary system; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PIK3C2G (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma). [provided by Alliance of Genome Resources, Apr 2022]

Pik3c2g Products(2)

mRNA Protein Name
NM_207683.3 NP_997566.2 phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform 1
NM_011084.2 NP_035214.2 phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform 2

Pik3c2g Protein Structure

C2A_PI3K_class_II

C2A_PI3K_class_II: cd04012 (537 - 697)

PI3Ka

PI3Ka: cl00271 (712 - 879)

PI3Kc_C2_gamma

PI3Kc_C2_gamma: cd05177 (885 - 1238)

PX_PI3K_C2_gamma

PX_PI3K_C2_gamma: cd06896 (1267 - 1367)

C2

C2: cl14603 (1389 - 1501)

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  • 1506 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 3-kinase C2 domain-containing subunit gamma

phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide

phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma

ptdIns-3-kinase C2 subunit gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10517 PIK3C2G Human Pre-designed siRNA Set A / Unkown
HY-RS10518 Pik3c2g Mouse Pre-designed siRNA Set A / Unkown
HY-RS10519 Pik3c2g Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pik3c2g NCBI NCBI:5288