Pip5k1a - phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha Gene

Also Known as Pipk5a; PI4P5K-I[a]; PIP5KIalpha; PIP5K1-alpha

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18720

Summary

Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Acts upstream of or within fibroblast migration and phosphatidylinositol biosynthetic process. Located in cytosol; nucleus; and ruffle membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PIP5K1A (phosphatidylinositol-4-phosphate 5-kinase type 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pip5k1a Products (2)

mRNA Protein Name
NM_001293707.1 NP_001280636.1 phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform 1
NM_008847.3 NP_032873.2 phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IDA
IDA: Inferred from direct assay
8798574 MGI
enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IGI
IGI: Inferred from genetic interaction
20622009 MGI
enables 1-phosphatidylinositol-4-phosphate 5-kinase activity IMP
IMP: Inferred from mutant phenotype
27739494 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14701839 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within fibroblast migration IMP
IMP: Inferred from mutant phenotype
15870270 MGI
acts upstream of or within phosphatidylinositol biosynthetic process IGI
IGI: Inferred from genetic interaction
20622009 MGI
acts upstream of or within phosphatidylinositol metabolic process IDA
IDA: Inferred from direct assay
8798574 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
20622009 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15870270 MGI
located in ruffle membrane IDA
IDA: Inferred from direct assay
15870270 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

  • 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase

  • 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha

  • phosphatidylinositol 4-phosphate 5-kinase type I alpha

  • ptdIns(4)P-5-kinase 1 alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70631 PIP5K1A Recombinant Human Active Lipid Kinase / Unkown
HY-RS10566 PIP5K1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19547 Pip5k1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26043 Pip5k1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pip5k1a NCBI NCBI:8394