2. Gene
  3. Plxna2 - plexin A2 Gene

Plxna2 - plexin A2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as OCT; Plxn2; PlexA2; mKIAA0463; 2810428A13Rik

Gene ID: 18845 | Gene type: protein coding

About Plxna2

Summary

Enables identical protein binding activity and semaphorin receptor activity. Involved in regulation of cell migration and semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including cerebellar granule cell precursor tangential migration; chordate embryonic development; and limb bud formation. Is integral component of plasma membrane. Is expressed in several structures, including genitourinary system; heart; lung; nervous system; and sensory organ. Orthologous to human PLXNA2 (plexin A2). [provided by Alliance of Genome Resources, Apr 2022]

Plxna2 Products(1)

mRNA Protein Name
NM_008882.2 NP_032908.2 plexin-A2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
20877282 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20877282 MGI
enables semaphorin receptor activity IGI
IGI: Inferred from genetic interaction
18327254 MGI
enables semaphorin receptor activity IMP
IMP: Inferred from mutant phenotype
20877282 MGI
enables semaphorin receptor activity IPI
IPI: Inferred from physical interaction
18327254 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: Inferred from direct assay
18327254 MGI
acts upstream of or within centrosome localization IMP
IMP: Inferred from mutant phenotype
18327254 MGI
acts upstream of or within cerebellar granule cell precursor tangential migration IMP
IMP: Inferred from mutant phenotype
18327254 MGI
involved in limb bud formation IEP
IEP: Inferred from expression pattern
19666519 MGI
involved in neural tube development IEP
IEP: Inferred from expression pattern
19666519 MGI
involved in pharyngeal system development IEP
IEP: Inferred from expression pattern
19666519 MGI
involved in regulation of cell migration IMP
IMP: Inferred from mutant phenotype
20877282 MGI
involved in semaphorin-plexin signaling pathway IMP
IMP: Inferred from mutant phenotype
20877282 MGI
involved in somitogenesis IEP
IEP: Inferred from expression pattern
19666519 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
20881961 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plexin-A2

plex 2

plexin-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10749 PLXNA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plxna2 NCBI NCBI:5362