Pou2f3 - POU domain, class 2, transcription factor 3 Gene

Also Known as Skin; Oct11; Otf11; Epoc-1; Otf-11; Skn-1a; Skn-li; Oct-11a; Skin-1a

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18988

Summary

Enables identical protein binding activity and sequence-specific DNA binding activity. Acts upstream of or within keratinocyte differentiation; positive regulation of transcription by RNA polymerase II; and wound healing. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; gut; skin; and thymus. Orthologous to human POU2F3 (POU class 2 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Pou2f3 Products (1)

mRNA Protein Name
NM_011139.2 NP_035269.2 POU domain, class 2, transcription factor 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
7682011 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
7682011 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8224904 MGI
Biological Process GO Annotation Evidence References Source
involved in cell differentiation IMP
IMP: Inferred from mutant phenotype
29216297 MGI
acts upstream of or within epidermis development IGI
IGI: Inferred from genetic interaction
9242494 MGI
acts upstream of or within keratinocyte differentiation IGI
IGI: Inferred from genetic interaction
9242494 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7682011 MGI
acts upstream of or within wound healing IMP
IMP: Inferred from mutant phenotype
9242494 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9242494 MGI
part of transcription regulator complex IDA
IDA: Inferred from direct assay
7682011 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

POU domain, class 2, transcription factor 3

  • oct-11

  • octamer-binding protein 11

  • octamer-binding transcription factor 11

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10899 POU2F3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pou2f3 NCBI NCBI:25833