Pou2f3 - POU domain, class 2, transcription factor 3 Gene

Mus musculus

Also known as Skin; Oct11; Otf11; Epoc-1; Otf-11; Skn-1a; Skn-li; Oct-11a; Skin-1a

Gene ID: 18988 | Gene type: protein coding

About Pou2f3

Summary

Enables identical protein binding activity and sequence-specific DNA binding activity. Acts upstream of or within keratinocyte differentiation; positive regulation of transcription by RNA polymerase II; and wound healing. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; gut; skin; and thymus. Orthologous to human POU2F3 (POU class 2 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Pou2f3 Products(1)

mRNA	Protein	Name
NM_011139.2	NP_035269.2	POU domain, class 2, transcription factor 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA binding	IDA IDA: Inferred from direct assay	7682011	MGI
enables identical protein binding	IPI IPI: Inferred from physical interaction	7682011	MGI
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	8224904	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in cell differentiation	IMP IMP: Inferred from mutant phenotype	29216297	MGI
acts upstream of or within epidermis development	IGI IGI: Inferred from genetic interaction	9242494	MGI
acts upstream of or within keratinocyte differentiation	IGI IGI: Inferred from genetic interaction	9242494	MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	7682011	MGI
acts upstream of or within wound healing	IMP IMP: Inferred from mutant phenotype	9242494	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	9242494	MGI
part of transcription regulator complex	IDA IDA: Inferred from direct assay	7682011	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

POU domain, class 2, transcription factor 3

oct-11	octamer-binding protein 11
octamer-binding transcription factor 11

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10899	POU2F3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pou2f3	NCBI	NCBI:25833

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