Ppp1cb - protein phosphatase 1 catalytic subunit beta Gene

Also Known as 1200010B19

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19046

Summary

Enables protein serine/threonine Phosphatase activity. Involved in circadian regulation of gene expression; entrainment of circadian clock by photoperiod; and protein dephosphorylation. Located in cytoplasm. Is expressed in cornea; lens epithelium; lens fiber; limb; and retina. Human ortholog(s) of this gene implicated in Noonan syndrome-like disorder with loose anagen hair 2. Orthologous to human PPP1CB (protein Phosphatase 1 catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1cb Products (1)

mRNA Protein Name
NM_172707.3 NP_766295.2 serine/threonine-protein phosphatase PP1-beta catalytic subunit

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables phosphatase activity IDA
IDA: Inferred from direct assay
21930935 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21471512 MGI
enables protein serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
14640981 MGI
Biological Process GO Annotation Evidence References Source
involved in circadian regulation of gene expression IDA
IDA: Inferred from direct assay
21930935 MGI
involved in entrainment of circadian clock by photoperiod IMP
IMP: Inferred from mutant phenotype
21712997 MGI
acts upstream of or within protein dephosphorylation IDA
IDA: Inferred from direct assay
14640981 MGI
involved in protein dephosphorylation IDA
IDA: Inferred from direct assay
21930935 MGI
involved in regulation of circadian rhythm IDA
IDA: Inferred from direct assay
21930935 MGI
involved in regulation of circadian rhythm IMP
IMP: Inferred from mutant phenotype
21712997 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21471512 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase PP1-beta catalytic subunit

  • PP-1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10974 PPP1CB Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp1cb NCBI NCBI:5500