2. Gene
  3. Prkcsh - protein kinase C substrate 80K-H Gene

Prkcsh - protein kinase C substrate 80K-H Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 80K-H; PKCSH

Gene ID: 19089 | Gene type: protein coding

About Prkcsh

Summary

Enables RNA binding activity and calcium ion binding activity. Acts upstream of or within several processes, including in utero embryonic development; liver development; and negative regulation of neuron projection development. Part of glucosidase II complex. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system gland. Used to study polycystic liver disease. Human ortholog(s) of this gene implicated in liver disease and polycystic liver disease. Orthologous to human PRKCSH (protein kinase C substrate 80K-H). [provided by Alliance of Genome Resources, Apr 2022]

Prkcsh Products(3)

mRNA Protein Name
NM_001293650.1 NP_001280579.1 glucosidase 2 subunit beta isoform 1 precursor
NM_001293651.1 NP_001280580.1 glucosidase 2 subunit beta isoform 2 precursor
NM_008925.2 NP_032951.1 glucosidase 2 subunit beta isoform 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables RNA binding IDA
IDA: Inferred from direct assay
16706842 MGI
enables calcium ion binding IDA
IDA: Inferred from direct assay
27462106 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9148925 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
21685914 MGI
acts upstream of or within liver development IGI
IGI: Inferred from genetic interaction
21685914 MGI
acts upstream of or within negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
22337885 MGI
acts upstream of or within nitrogen cycle metabolic process IGI
IGI: Inferred from genetic interaction
21685914 MGI
Cellular Component GO Annotation Evidence Reference Source
part of glucosidase II complex IDA
IDA: Inferred from direct assay
27462106 MGI
part of glucosidase II complex IPI
IPI: Inferred from physical interaction
9148925 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glucosidase 2 subunit beta

alpha glucosidase II, beta-subunit

carbohydrate processing enzyme of the endoplasmic reticulum

glucosidase II beta-subunit

hepatocystin

protein kinase C substrate 60.1 kDa protein heavy chain

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11140 PRKCSH Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkcsh NCBI NCBI:5589