Psme1 - proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) Gene

Also Known as PA28a

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19186

Summary

Contributes to endopeptidase activator activity. Acts upstream of or within antigen processing and presentation of exogenous antigen. Predicted to be part of Proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including adipose tissue; alimentary system; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human PSME1 (Proteasome activator subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Psme1 Products (1)

mRNA Protein Name
NM_011189.1 NP_035319.1 proteasome activator complex subunit 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
contributes to endopeptidase activator activity IDA
IDA: Inferred from direct assay
15944286 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15944286 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within antigen processing and presentation of exogenous antigen IMP
IMP: Inferred from mutant phenotype
15944286 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proteasome activator complex subunit 1

  • 11S regulator complex subunit alpha

  • PA28 alpha subunit

  • PA28alpha

  • REG-alpha

  • activator of multicatalytic protease subunit 1

  • protease (prosome, macropain) 28 subunit, alpha

  • proteasome (prosome, macropain) 28 subunit, alpha

  • proteasome activator 28 subu

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-158301 MY-1B Inhibitor 99.94% Unkown
HY-162965 Immunoproteasome activator 1 Activator 99.67% Unkown
HY-RS11331 PSME1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20088 Psme1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26591 Psme1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psme1 NCBI NCBI:5720