Atp12a - ATPase, H+/K+ transporting, nongastric, alpha polypeptide Gene

Also Known as cHKA; Atp1al1; HKalpha2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 192113

Summary

Predicted to enable P-type potassium:proton transporter activity and P-type sodium:potassium-exchanging transporter activity. Acts upstream of or within potassium ion homeostasis and regulation of pH. Located in basolateral plasma membrane. Is expressed in several structures, including gut; metanephros; pituitary gland; reproductive system; and thymus. Orthologous to human ATP12A (ATPase H+/K+ transporting non-gastric alpha2 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Atp12a Products (1)

mRNA Protein Name
NM_138652.2 NP_619593.2 potassium-transporting ATPase alpha chain 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15647390 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within potassium ion homeostasis IMP
IMP: Inferred from mutant phenotype
9449685 MGI
acts upstream of or within regulation of pH IMP
IMP: Inferred from mutant phenotype
16525125 MGI
Cellular Component GO Annotation Evidence References Source
located in basolateral plasma membrane IMP
IMP: Inferred from mutant phenotype
16525125 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium-transporting ATPase alpha chain 2

  • ATPase H+K+-transporting, alpha 2

  • HK alpha 2

  • non-gastric H(+)/K(+) ATPase subunit alpha

  • non-gastric Na(+)/K(+) ATPase subunit alpha

  • proton pump

  • sodium pump

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01177 ATP12A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp12a NCBI NCBI:479