2. Gene
  3. Pigl - phosphatidylinositol glycan anchor biosynthesis, class L Gene

Pigl - phosphatidylinositol glycan anchor biosynthesis, class L Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 192263 | Gene type: protein coding

About Pigl

Summary

Predicted to enable N-acetylglucosaminylphosphatidylinositol deacetylase activity. Involved in GPI anchor biosynthetic process. Located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in CHIME syndrome. Orthologous to human PIGL (phosphatidylinositol glycan anchor biosynthesis class L). [provided by Alliance of Genome Resources, Apr 2022]

Pigl Products(1)

mRNA Protein Name
NM_138901.2 NP_620256.1 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables N-acetylglucosaminylphosphatidylinositol deacetylase activity IDA
IDA: Inferred from direct assay
10085243 RGD
Biological Process GO Annotation Evidence Reference Source
involved in GPI anchor biosynthetic process IDA
IDA: Inferred from direct assay
9188481 RGD
Cellular Component GO Annotation Evidence Reference Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
9188481 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

PIG-L

phosphatidylinositol glycan, class L

phosphatidylinositol-glycan biosynthesis class L protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10494 PIGL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pigl NCBI NCBI:9487