1. Gene
  2. Rapgef6 - Rap guanine nucleotide exchange factor (GEF) 6 Gene

Rapgef6 - Rap guanine nucleotide exchange factor (GEF) 6 Gene

Mus musculus

Also known as Ragef2; Pdzgef2; PDZ-GEF2; RA-GEF-2; mKIAA4052; A530068K01; C030018K18Rik

Gene ID: 192786 | Gene type: protein coding

About Rapgef6

Summary

Predicted to enable several functions, including GTP-dependent protein binding activity; guanyl-nucleotide exchange factor activity; and phosphatidic acid binding activity. Predicted to be involved in microvillus assembly; positive regulation of GTPase activity; and protein localization to plasma membrane. Predicted to be located in several cellular components, including apical plasma membrane; centrosome; and endocytic vesicle. Is expressed in nervous system. Orthologous to human RAPGEF6 (Rap guanine nucleotide exchange factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Rapgef6 Products(5)

mRNA Protein Name
NM_001252494.1 NP_001239423.1 rap guanine nucleotide exchange factor 6 isoform 1
NM_001252496.1 NP_001239425.1 rap guanine nucleotide exchange factor 6 isoform 3
NM_001252497.1 NP_001239426.1 rap guanine nucleotide exchange factor 6 isoform 4
NM_001252498.1 NP_001239427.1 rap guanine nucleotide exchange factor 6 isoform 5
NM_175258.4 NP_780467.2 rap guanine nucleotide exchange factor 6 isoform 2
Protein Preferred Names Protein Names

rap guanine nucleotide exchange factor 6

PDZ domain containing guanine nucleotide exchange factor (GEF) 2

PDZ domain containing guanine nucleotide exchange factor(GEF)1

rap guanine nucleotide exchange factor 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Rapgef6 NCBI NCBI:51735