Rab18 - RAB18, member RAS oncogene family Gene

Mus musculus

Gene ID: 19330 | Gene type: protein coding

About Rab18

Summary

This gene encodes a member of the Ras-related small GTPases, which regulate membrane trafficking in organelles and transport vesicles. This protein is expressed predominantly in lipid droplets, organelles that store neutral lipids, and is proposed to play a role in lipolysis and lipogenesis. In humans mutations in this gene are associated with Warburg micro syndrome type 3. A pseudogene of this gene is located on chromosome X. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Rab18 Products(2)

mRNA	Protein	Name
NM_001278447.1	NP_001265376.1	ras-related protein Rab-18 isoform 1
NM_181070.6	NP_851415.1	ras-related protein Rab-18 isoform 2 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in import into nucleus	IMP IMP: Inferred from mutant phenotype	26021350	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ras-related protein Rab-18

GTP-binding protein Rab18

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11526	RAB18 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rab18	NCBI	NCBI:22931

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