Rab18 - RAB18, member RAS oncogene family Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19330

Summary

This gene encodes a member of the Ras-related small GTPases, which regulate membrane trafficking in organelles and transport vesicles. This protein is expressed predominantly in lipid droplets, organelles that store neutral lipids, and is proposed to play a role in lipolysis and lipogenesis. In humans mutations in this gene are associated with Warburg micro syndrome type 3. A pseudogene of this gene is located on chromosome X. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Rab18 Products (2)

mRNA Protein Name
NM_001278447.1 NP_001265376.1 ras-related protein Rab-18 isoform 1
NM_181070.6 NP_851415.1 ras-related protein Rab-18 isoform 2 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in import into nucleus IMP
IMP: Inferred from mutant phenotype
26021350 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-18

  • GTP-binding protein Rab18

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11526 RAB18 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab18 NCBI NCBI:22931