2. Gene
  3. Rab23 - RAB23, member RAS oncogene family Gene

Rab23 - RAB23, member RAS oncogene family Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as opb; opb2

Gene ID: 19335 | Gene type: protein coding

About Rab23

Summary

Predicted to enable GTPase activity. Involved in dorsal/ventral neural tube patterning. Acts upstream of or within several processes, including embryonic morphogenesis; regulation of smoothened signaling pathway; and spinal cord dorsal/ventral patterning. Located in endosome membrane and plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in Carpenter syndrome. Orthologous to human RAB23 (RAB23, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab23 Products(2)

mRNA Protein Name
NM_001159729.1 NP_001153201.1 ras-related protein Rab-23
NM_008999.4 NP_033025.2 ras-related protein Rab-23
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in dorsal/ventral neural tube patterning IMP
IMP: Inferred from mutant phenotype
7720556 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
9636176 MGI
acts upstream of or within negative regulation of proteolysis IMP
IMP: Inferred from mutant phenotype
16364285 MGI
acts upstream of or within nervous system development IMP
IMP: Inferred from mutant phenotype
11449277 MGI
acts upstream of or within neural tube closure IMP
IMP: Inferred from mutant phenotype
9636176 MGI
involved in neural tube closure IMP
IMP: Inferred from mutant phenotype
7720556 MGI
acts upstream of proteolysis IMP
IMP: Inferred from mutant phenotype
16364285 MGI
acts upstream of or within regulation of smoothened signaling pathway IGI
IGI: Inferred from genetic interaction
19004860 MGI
acts upstream of or within signal transduction IMP
IMP: Inferred from mutant phenotype
11449277 MGI
acts upstream of or within spinal cord dorsal/ventral patterning IGI
IGI: Inferred from genetic interaction
14603322 MGI
acts upstream of or within spinal cord dorsal/ventral patterning IMP
IMP: Inferred from mutant phenotype
15755804 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endosome membrane IDA
IDA: Inferred from direct assay
16463280 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
16463280 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-23

open brain 2

protein open brain

rab-15

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11533 RAB23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab23 NCBI NCBI:51715