Rab4a - RAB4A, member RAS oncogene family Gene

Also Known as Rab4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19341

Summary

Predicted to enable several functions, including ATPase binding activity; guanyl ribonucleotide binding activity; and ionotropic glutamate receptor binding activity. Acts upstream of or within protein transport; regulation of endocytosis; and small GTPase mediated signal transduction. Located in endosome. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; gut; and liver and biliary system. Orthologous to human RAB4A (RAB4A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab4a Products (1)

mRNA Protein Name
NM_009003.4 NP_033029.2 ras-related protein Rab-4A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11172003 MGI
Biological Process GO Annotation Evidence References Source
involved in neurotransmitter receptor transport postsynaptic membrane to endosome IDA
IDA: Inferred from direct assay
24217640 MGI
involved in neurotransmitter receptor transport postsynaptic membrane to endosome IMP
IMP: Inferred from mutant phenotype
24217640 MGI
acts upstream of or within protein transport IDA
IDA: Inferred from direct assay
11172003 MGI
acts upstream of or within regulation of endocytosis IDA
IDA: Inferred from direct assay
11172003 MGI
acts upstream of or within small GTPase-mediated signal transduction IDA
IDA: Inferred from direct assay
11172003 MGI
involved in vesicle-mediated transport in synapse IDA
IDA: Inferred from direct assay
24217640 MGI
involved in vesicle-mediated transport in synapse IMP
IMP: Inferred from mutant phenotype
24217640 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18656450 MGI
located in endosome IDA
IDA: Inferred from direct assay
11172003 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24217640 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
24217640 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-4A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11569 RAB4A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab4a NCBI NCBI:5867