2. Gene
  3. Dennd5a - DENN domain containing 5A Gene

Dennd5a - DENN domain containing 5A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ORF37; Rab6ip1; mKIAA1091; 1500012B19Rik

Gene ID: 19347 | Gene type: protein coding

About Dennd5a

Summary

Enables small GTPase binding activity. Predicted to be involved in negative regulation of neuron projection development and retrograde transport, endosome to Golgi. Located in Golgi apparatus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 49. Orthologous to human DENND5A (DENN domain containing 5A). [provided by Alliance of Genome Resources, Apr 2022]

Dennd5a Products(2)

mRNA Protein Name
NM_001311139.1 NP_001298068.1 DENN domain-containing protein 5A isoform 2
NM_021494.1 NP_067469.1 DENN domain-containing protein 5A isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19141279 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
7631419 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
19141279 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DENN domain-containing protein 5A

DENN/MADD domain containing 5A

Rab6 interacting protein 1

rab6-interacting protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03690 DENND5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dennd5a NCBI NCBI:23258