Rad23b - RAD23 homolog B, nucleotide excision repair protein Gene

Mus musculus

Also known as p58; HR23B; mHR23B; 0610007D13Rik

Gene ID: 19359 | Gene type: protein coding

About Rad23b

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within cellular response to DNA damage stimulus; cellular response to interleukin-7; and spermatogenesis. Located in cytoplasm and nucleus. Is expressed in central nervous system; reproductive system; and retina nuclear layer. Orthologous to human RAD23B (RAD23 homolog B, nucleotide excision repair protein). [provided by Alliance of Genome Resources, Apr 2022]

Rad23b Products(1)

mRNA	Protein	Name
NM_009011.4	NP_033037.2	UV excision repair protein RAD23 homolog B

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	25901318	MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding	IPI IPI: Inferred from physical interaction	25901318	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	15358861	MGI
enables transcription cis-regulatory region binding	IDA IDA: Inferred from direct assay	25901318	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within DNA damage response	IDA IDA: Inferred from direct assay	12815074	MGI
acts upstream of or within cellular response to interleukin-7	IDA IDA: Inferred from direct assay	29581031	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	11809813	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	22431748	MGI
located in nucleus	IDA IDA: Inferred from direct assay	22431748	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

UV excision repair protein RAD23 homolog B

RAD23b homolog

XP-C repair-complementing complex 58 kDa protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11601	RAD23B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rad23b	NCBI	NCBI:5887

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