Rad51d - RAD51 paralog D Gene

Also Known as TRAD; R51H3; Rad51l3; Trad-d5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19364

Summary

This gene belongs to the RAD51 gene family whose products play a major role in homologous recombination and DNA repair. The encoded protein interacts with Other proteins of this family, including Rad51b, Rad51c and Xrcc2, and plays an essential role in both DNA repair and telomere maintenance. In humans, germline mutations in this gene may be associated with predisposition to ovarian Cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Rad51d Products (5)

mRNA Protein Name
NM_001277938.1 NP_001264867.1 DNA repair protein RAD51 homolog 4 isoform 2
NM_001277939.1 NP_001264868.1 DNA repair protein RAD51 homolog 4 isoform 3
NM_001277941.1 NP_001264870.1 DNA repair protein RAD51 homolog 4 isoform 4
NM_001277942.1 NP_001264871.1 DNA repair protein RAD51 homolog 4 isoform 5
NM_011235.4 NP_035365.1 DNA repair protein RAD51 homolog 4 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20813759 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within DNA damage response IMP
IMP: Inferred from mutant phenotype
20813759 MGI
acts upstream of or within chromosome organization IMP
IMP: Inferred from mutant phenotype
15781618 MGI
acts upstream of or within interstrand cross-link repair IMP
IMP: Inferred from mutant phenotype
15781618 MGI
acts upstream of or within regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
20813759 MGI
involved in telomere maintenance IGI
IGI: Inferred from genetic interaction
15109494 MGI
Cellular Component GO Annotation Evidence References Source
located in chromosome, telomeric region IDA
IDA: Inferred from direct assay
15109494 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA repair protein RAD51 homolog 4

  • RAD51 homolog D

  • RAD51-like 3

  • TRAD/RAD51L3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11609 RAD51D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rad51d NCBI NCBI:5892