Raet1b - retinoic acid early transcript beta Gene

Also Known as Rae1b; RAE-1beta

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19369

Summary

Enables natural killer cell lectin-like receptor binding activity. Acts upstream of or within several processes, including positive regulation of immune response; positive regulation of leukocyte activation; and response to bacterium. Located in external side of plasma membrane. Is anchored component of external side of plasma membrane. Is expressed in several structures, including branchial arch; heart; liver; placenta; and spleen. Orthologous to several human genes including ULBP2 (UL16 binding protein 2); RAET1E (retinoic acid early transcript 1E); and RAET1G (retinoic acid early transcript 1G). [provided by Alliance of Genome Resources, Apr 2022]

Raet1b Products (1)

mRNA Protein Name
NM_009017.1 NP_033043.1 retinoic acid early-inducible protein 1-beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables natural killer cell lectin-like receptor binding IDA
IDA: Inferred from direct assay
10894171 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12645935 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to exogenous dsRNA IDA
IDA: Inferred from direct assay
14764662 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
14764662 MGI
acts upstream of or within defense response to bacterium IDA
IDA: Inferred from direct assay
14764662 MGI
acts upstream of or within positive regulation of immune response to tumor cell IDA
IDA: Inferred from direct assay
12645935 MGI
acts upstream of or within positive regulation of macrophage activation IDA
IDA: Inferred from direct assay
12645935 MGI
acts upstream of or within positive regulation of natural killer cell activation IDA
IDA: Inferred from direct assay
12645935 MGI
acts upstream of or within positive regulation of nitric oxide biosynthetic process IDA
IDA: Inferred from direct assay
12645935 MGI
acts upstream of or within positive regulation of type II interferon production IDA
IDA: Inferred from direct assay
12645935 MGI
acts upstream of or within susceptibility to natural killer cell mediated cytotoxicity IDA
IDA: Inferred from direct assay
12645935 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
12645935 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10894171 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retinoic acid early-inducible protein 1-beta

  • RAE-1-beta

  • Rae-1 beta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11618 RAET1E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20588 Raet1e Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27096 Raet1e Rat Pre-designed siRNA Set A Pre-designed Set / Unkown