Klf11 - Kruppel-like factor 11 Gene

Also Known as Tieg2; Tieg3; Tieg2b; 9830142A17; D12Ertd427e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 194655

Summary

Enables DNA-binding transcription factor activity. Involved in negative regulation of transcription, DNA-templated. Predicted to be located in cytosol; focal adhesion; and nuclear body. Is expressed in several structures, including brain; early conceptus; genitourinary system; liver; and sensory organ. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Orthologous to human KLF11 (Kruppel like factor 11). [provided by Alliance of Genome Resources, Apr 2022]

Klf11 Products (1)

mRNA Protein Name
NM_178357.3 NP_848134.1 Krueppel-like factor 11

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
14697507 MGI
Biological Process GO Annotation Evidence References Source
NOT acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
15607700 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
14697507 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Krueppel-like factor 11

  • TGFB inducible early growth response 2

  • TGFB inducible early growth response 3

  • TGFB-inducible early growth response protein 2b

  • TGFB-inducible early growth response protein 3

  • TIEG-3

  • transforming growth factor-beta-inducible early growth response protei

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07332 KLF11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klf11 NCBI NCBI:8462