Zzef1 - zinc finger, ZZ-type with EF hand domain 1 Gene

Also Known as NSPA; mKIAA0399; 8430405D05Rik; C130099L13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 195018

Summary

Enables ubiquitin-like protein Ligase activity. Acts upstream of or within several processes, including glutamatergic synaptic transmission; regulation of peptidyl-tyrosine phosphorylation; and visual learning. Located in cell surface; postsynapse; and presynaptic active zone. Is expressed in several structures, including adipose tissue; alimentary system; immune system; nervous system; and reproductive system. Orthologous to human ZZEF1 (zinc finger ZZ-type and EF-hand domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Zzef1 Products (1)

mRNA Protein Name
NM_001045536.2 NP_001039001.1 zinc finger ZZ-type and EF-hand domain-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ubiquitin-like protein ligase activity IMP
IMP: Inferred from mutant phenotype
33158444 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
33158444 MGI
acts upstream of or within protein ubiquitination IMP
IMP: Inferred from mutant phenotype
33158444 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IMP
IMP: Inferred from mutant phenotype
33158444 MGI
acts upstream of or within regulation of synaptic plasticity IMP
IMP: Inferred from mutant phenotype
25709106 MGI
acts upstream of or within synaptic transmission, glutamatergic IMP
IMP: Inferred from mutant phenotype
25709106 MGI
acts upstream of or within visual learning IMP
IMP: Inferred from mutant phenotype
25709106 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
25709106 MGI
located in postsynapse IDA
IDA: Inferred from direct assay
25709106 MGI
located in presynaptic active zone IDA
IDA: Inferred from direct assay
25709106 MGI
located in synapse IDA
IDA: Inferred from direct assay
33158444 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger ZZ-type and EF-hand domain-containing protein 1

  • KIAA0399-like protein human

  • neuronal superface P antigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16216 ZZEF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zzef1 NCBI NCBI:23140