Rom1 - rod outer segment membrane protein 1 Gene

Also Known as Rom-1; Rosp1; M101156; Tspan23; Rgsc1156

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19881

Summary

Enables protein homodimerization activity. Acts upstream of or within several processes, including detection of light stimulus involved in visual perception; protein complex oligomerization; and retina development in camera-type eye. Located in photoreceptor outer segment membrane. Is expressed in photoreceptor layer; photoreceptor layer outer segment; and retina. Human ortholog(s) of this gene implicated in retinitis pigmentosa 7. Orthologous to human ROM1 (retinal outer segment membrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Rom1 Products (1)

mRNA Protein Name
NM_009073.4 NP_033099.3 rod outer segment membrane protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20055437 MGI
enables protein homodimerization activity IPI
IPI: Inferred from physical interaction
20055437 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within camera-type eye photoreceptor cell differentiation IMP
IMP: Inferred from mutant phenotype
20300562 MGI
acts upstream of or within detection of light stimulus involved in visual perception IGI
IGI: Inferred from genetic interaction
28053051 MGI
acts upstream of or within photoreceptor cell outer segment organization IGI
IGI: Inferred from genetic interaction
28053051 MGI
acts upstream of or within photoreceptor cell outer segment organization IMP
IMP: Inferred from mutant phenotype
28053051 MGI
acts upstream of or within protein heterooligomerization IPI
IPI: Inferred from physical interaction
20055437 MGI
acts upstream of or within protein homooligomerization IPI
IPI: Inferred from physical interaction
20055437 MGI
acts upstream of or within protein localization to photoreceptor outer segment IDA
IDA: Inferred from direct assay
28053051 MGI
acts upstream of or within protein localization to photoreceptor outer segment IMP
IMP: Inferred from mutant phenotype
28053051 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20300562 MGI
acts upstream of or within retina development in camera-type eye IGI
IGI: Inferred from genetic interaction
28053051 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
28053051 MGI
acts upstream of or within retina morphogenesis in camera-type eye IMP
IMP: Inferred from mutant phenotype
20300562 MGI
acts upstream of or within retina vasculature development in camera-type eye IMP
IMP: Inferred from mutant phenotype
20300562 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
20592197 MGI
located in photoreceptor outer segment membrane IDA
IDA: Inferred from direct assay
18654668 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rod outer segment membrane protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12121 ROM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18971 Rom1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25461 Rom1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rom1 NCBI NCBI:6094