Rpl26 - ribosomal protein L26 Gene

Also Known as SIG-20

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19941

Summary

Predicted to enable mRNA 5'-UTR binding activity. Predicted to be a structural constituent of ribosome. Involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; cellular response to ionizing radiation; and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in cytosolic ribosome; nucleolus; and nucleoplasm. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Orthologous to human RPL26 (ribosomal protein L26). [provided by Alliance of Genome Resources, Apr 2022]

Rpl26 Products (1)

mRNA Protein Name
NM_009080.2 NP_033106.1 60S ribosomal protein L26

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21045808 MGI
enables structural constituent of ribosome IDA
IDA: Inferred from direct assay
36517592 MGI
Biological Process GO Annotation Evidence References Source
involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IDA
IDA: Inferred from direct assay
16213212 MGI
involved in cellular response to ionizing radiation IMP
IMP: Inferred from mutant phenotype
16213212 MGI
involved in positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
IMP: Inferred from mutant phenotype
16213212 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
36517592 MGI
part of cytosolic large ribosomal subunit IDA
IDA: Inferred from direct assay
36517592 MGI
part of cytosolic large ribosomal subunit IPI
IPI: Inferred from physical interaction
36517592 MGI
is active in synapse EXP
EXP: Inferred from Experiment
25211037 MGI
is active in synapse IDA
IDA: Inferred from direct assay
25211037 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

60S ribosomal protein L26

  • silica-induced gene 20 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12178 RPL26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12179 RPL26L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22784 Rpl26 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29298 Rpl26 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rpl26 NCBI NCBI:6154