2. Gene
  3. Polr1c - polymerase (RNA) I polypeptide C Gene

Polr1c - polymerase (RNA) I polypeptide C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 40kDa; RPA40; Polr1e; Rpo1-1

Gene ID: 20016 | Gene type: protein coding

About Polr1c

Summary

Predicted to enable DNA binding activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription, DNA-templated. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; genitourinary system; midbrain; respiratory system; and telencephalon. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Orthologous to human POLR1C (RNA polymerase I and III subunit C). [provided by Alliance of Genome Resources, Apr 2022]

Polr1c Products(1)

mRNA Protein Name
NM_009085.2 NP_033111.2 DNA-directed RNA polymerases I and III subunit RPAC1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
part of RNA polymerase I complex IDA
IDA: Inferred from direct assay
7929437 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerases I and III subunit RPAC1

AC40

DNA-directed RNA polymerase I subunit C

DNA-directed RNA polymerases I and III 40 kDa polypeptide

RNA polymerase 1-1 (40 kDa subunit)

RNA polymerases I and III subunit AC1

RPC40

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10839 POLR1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10840 POLR1D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr1c NCBI NCBI:9533