Polr1c - polymerase (RNA) I polypeptide C Gene

Also Known as 40kDa; RPA40; Polr1e; Rpo1-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20016

Summary

Predicted to enable DNA binding activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription, DNA-templated. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; genitourinary system; midbrain; respiratory system; and telencephalon. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Orthologous to human POLR1C (RNA polymerase I and III subunit C). [provided by Alliance of Genome Resources, Apr 2022]

Polr1c Products (1)

mRNA Protein Name
NM_009085.2 NP_033111.2 DNA-directed RNA polymerases I and III subunit RPAC1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
part of RNA polymerase I complex IDA
IDA: Inferred from direct assay
7929437 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-directed RNA polymerases I and III subunit RPAC1

  • AC40

  • DNA-directed RNA polymerase I subunit C

  • DNA-directed RNA polymerases I and III 40 kDa polypeptide

  • RNA polymerase 1-1 (40 kDa subunit)

  • RNA polymerases I and III subunit AC1

  • RPC40

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10839 POLR1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10840 POLR1D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Polr1c NCBI NCBI:9533