2. Gene
  3. Nkx1-2 - NK1 homeobox 2 Gene

Nkx1-2 - NK1 homeobox 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sax1; Nkx-1.1; Nkx-1.2

Gene ID: 20231 | Gene type: protein coding

About Nkx1-2

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; hemolymphoid system; male reproductive system; and primitive streak. Orthologous to human NKX1-2 (NK1 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Nkx1-2 Products(1)

mRNA Protein Name
NM_009123.2 NP_033149.1 NK1 transcription factor-related protein 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9748262 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NK1 transcription factor-related protein 2

NK1 transcription factor related, locus 2

homeobox protein Nkx1.2E427

homeobox protein SAX-1

spinal cord axial homeobox gene 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09326 NKX1-2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkx1-2 NCBI NCBI:390010