Scn7a - sodium channel, voltage-gated, type VII, alpha Gene

Mus musculus

Also known as NaG; Nax; Nav2; Scn6a; Nav2.3; 1110034K09Rik

Gene ID: 20272 | Gene type: protein coding

About Scn7a

Summary

Enables Sodium Channel activity. Acts upstream of or within response to bacterium and sodium ion homeostasis. Located in glial cell projection and plasma membrane. Is expressed in heart and heart ventricle. Orthologous to human SCN7A (sodium voltage-gated channel alpha subunit 7). [provided by Alliance of Genome Resources, Apr 2022]

Scn7a Products(1)

mRNA	Protein	Name
NM_009135.2	NP_033161.2	sodium channel protein type 7 subunit alpha

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables sodium channel activity	IDA IDA: Inferred from direct assay	16223844	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cellular homeostasis	IDA IDA: Inferred from direct assay	16223844	MGI
acts upstream of or within cellular homeostasis	IMP IMP: Inferred from mutant phenotype	16223844	MGI
involved in osmosensory signaling pathway	IMP IMP: Inferred from mutant phenotype	17408578	MGI
acts upstream of or within response to bacterium	IEP IEP: Inferred from expression pattern	23012479	MGI
acts upstream of or within sodium ion homeostasis	IDA IDA: Inferred from direct assay	16223844	MGI
acts upstream of or within sodium ion homeostasis	IMP IMP: Inferred from mutant phenotype	16223844	MGI
involved in sodium ion homeostasis	IMP IMP: Inferred from mutant phenotype	17408578	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in glial cell projection	IDA IDA: Inferred from direct assay	16223844	MGI
is active in plasma membrane	IDA IDA: Inferred from direct assay	17408578	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	16223844	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sodium channel protein type 7 subunit alpha

sodium channel, voltage-gated, type VI, alpha polypeptide

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12544	SCN7A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Scn7a	NCBI	NCBI:6332

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