Sec23a - SEC23 homolog A, COPII coat complex component Gene

Also Known as Msec23; Sec23r

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20334

Summary

Predicted to enable GTPase activator activity and zinc ion binding activity. Involved in protein localization to plasma membrane. Located in COPII-coated ER to Golgi transport vesicle; Golgi membrane; and perinuclear region of cytoplasm. Is expressed in central nervous system; craniocervical region bone; retina; and thoracic segment skeleton. Human ortholog(s) of this gene implicated in craniolenticulosutural dysplasia. Orthologous to human SEC23A (SEC23 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Apr 2022]

Sec23a Products (2)

mRNA Protein Name
NM_001361956.1 NP_001348885.1 protein transport protein Sec23A
NM_009147.2 NP_033173.2 protein transport protein Sec23A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15899885 MGI
Biological Process GO Annotation Evidence References Source
involved in protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
27354378 MGI
Cellular Component GO Annotation Evidence References Source
located in COPII-coated ER to Golgi transport vesicle IDA
IDA: Inferred from direct assay
21187406 MGI
located in Golgi membrane IDA
IDA: Inferred from direct assay
11042173 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15642376 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein transport protein Sec23A

  • SEC23-related protein A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12612 SEC23A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sec23a NCBI NCBI:10484